I would much prefer that candidates keep things that I am not supposed to consider in the hiring process out of their interview.  For instance rather than being specific, you might indicate that for personal reasons or perhaps  health reasons you foresee needing a chunk of time off. Explain that you understand this is important for your potential employer to know. If you are moving to be nearer family members, that's one thing.  If you are going to grill an employer on how much time they allow you to take off for family matters in an initial interview you will come across as someone less interested in what they can contribute to the organization and more interested in what they can get from it.
 
Many employers are up front about benefits and when they are I often feel it is premature.  To me it gets the interview rather off track of the position itself and my qualifications for it. Too, I am focused enough about the latter two points that I do not retain much of what they have to say about the benefits.  Benefit information is available outside the interview in most organizations. If it is important to a candidate (someone in this thread said that they didn't have time to waste waiting until the negotiations phase to discover them)  it is probably something the candidate should consider screening positions for this before making application to them.

If you want to know about the flexibility of hours, ask about the flexibility of hours. Don't elaborate as to why. Sometimes I need to deal with a service person, sometimes I need to take an animal to the vet. Perhaps I want an afternoon off for a dog show. You may need to take a child to the doctor. You may want to go to a school program.  I might need dialysis.
 
 
 
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